Our lab is committed to improving the health of poultry through research on the prevention, control and diagnosis of infectious bursal disease (IBD). This disease was first described in the USA near the town of Gumboro, Delaware and thus is also known as Gumboro disease. IBD is a highly contagious immunosuppressive disease of chickens that is found worldwide and causes a major economic impact on egg and meat production. We are working to control and prevent the spread of IBD, which is caused by infectious bursal disease virus (IBDV).
The pathogenic strains of IBDV include classic virulent (cvIBDV), sub-clinical (scIBDV), and very virulent (vvIBDV). There are also naturally attenuated strains of the virus. All three pathogenic strains of IBDV cause immune suppression leading to secondary infections and a failure to produce an immune response to vaccines. cvIBDV causes a high morbidity and low mortality disease while scIBDV causes very little morbidity and no mortality. vvIBDV causes an acute disease in chickens characterized by high morbidity and high mortality. These viruses are economically devastating for the $30 billion US poultry industry and threaten the 15,000 jobs in Ohio that are associated with this industry.
Research in our lab focuses on three specific areas: disease control, epidemiology, and pathogenicity. Please see the lab page for more information on current research.
Dr. Jackwood is also the Director of the OARDC Research Internship Program (ORIP) which provides research experiences for incoming junior and senior high school students and college undergraduates. Please see the above link for more information on this program.
Dr. Jackwood is the founder of LARAD, Inc., a self-directed start up with an exclusive worldwide license from The Ohio State University for the IP developed by Dr. Jackwood. LARAD was formed to develop platform VLP technology specifically to address vaccines and diagnostics for animal diseases.