Dr. Daral Jackwood

Professor

Food Animal Health Research Program
Edgington Hall
OARDC Wooster, OH 44691
Phone: (330)-263-3964
Fax: 330-263-3760
Email: jackwood.2@osu.edu


Jackwood Laboratory

Biographical Information

  • BS, 1978, The University of Delaware, Newark, DE
  • MS, 1980, The Ohio State University, Columbus, OH
  • PhD, 1982, The Ohio State University, Columbus, OH

Research Area

Our lab is committed to improving the health of poultry through research on the prevention, control and diagnosis of infectious bursal disease (IBD). This disease was first described in the USA near the town of Gumboro, Delaware and thus is also known as Gumboro disease. IBD is a highly contagious immunosuppressive disease of chickens that is found worldwide and causes a major economic impact on egg and meat production. We are working to control and prevent the spread of IBD, which is caused by infectious bursal disease virus (IBDV).

The pathogenic strains of IBDV include classic virulent (cvIBDV), sub-clinical (scIBDV), and very virulent (vvIBDV). There are also naturally attenuated strains of the virus. All three pathogenic strains of IBDV cause immune suppression leading to secondary infections and a failure to produce an immune response to vaccines. cvIBDV causes a high morbidity and low mortality disease while scIBDV causes very little morbidity and no mortality. vvIBDV causes an acute disease in chickens characterized by high morbidity and high mortality. These viruses are economically devastating for the $30 billion US poultry industry and threaten the 15,000 jobs in Ohio that are associated with this industry.

Research in our lab focuses on three specific areas: disease control, epidemiology, and pathogenicity. Please see the lab page for more information on current research.

Dr. Jackwood is also the Director of the OARDC Research Internship Program (ORIP) which provides research experiences for incoming junior and senior high school students and college undergraduates. Please see the above link for more information on this program.

Honors and Other Activities

2016 OARDC Director’s Innovator of the Year Award

Dr. Jackwood is the founder of LARAD, Inc., a self-directed start up with an exclusive worldwide license from The Ohio State University for the IP developed by Dr. Jackwood. LARAD was formed to develop platform VLP technology specifically to address vaccines and diagnostics for animal diseases.


Selected Publications

2016

  1. Binjawadagi B, Lakshmanappa YS, Longchao Z, Dhakal S, Hiremath J, Ouyang K, Shyu D, Arcos J, Pengcheng S, Gilbertie A, Zuckermann F, Torrelles J, Jackwood D, Fang Y, Renukaradhya GJ. 2016. Development of a porcine reproductive and respiratory syndrome virus-like-particle-based vaccine and evaluation of its immunogenicity in pigs. Arch Virol. Jun;161(6):1579-89.
  2. Gelb J Jr, Jackwood DJ, Brannick EM, and Ladman BS. 2016. Efficacy of Recombinant HVT-IBD Vaccines Administered to Broiler Chicks from a Single Breeder Flock at 30 and 60 Weeks of Age. Avian Dis. 60:603-12.
  3. Jackwood DJ. 2016. Advances in vaccine research against economically important viral diseases of food animals: Infectious bursal disease virus. Vet Microbiol. 2016 Nov 22. pii: S0378-1135(16)30689-7.
  4. Silva MS, Bertran K, Moresco K, Jackwood DJ, Swayne DE. 2016. Infection with Some Infectious Bursal Disease Virus Pathotypes Produces Virus in Chicken Muscle Tissue and the Role of Humoral Immunity as a Mitigation Strategy. Avian Dis. 60:758-764.
  5. Nwagbo IO, Shittu I, Nwosuh CI, Ezeifeka GO, Odibo FJ, Michel LO, Jackwood DJ. 2016.Molecular characterization of field infectious bursal disease virus isolates from Nigeria. Vet World. 9:1420-1428.

2014

  1. Amin OG and Jackwood DJ. 2014. Identification and molecular analysis of infectious bursal disease in broiler farms in the Kurdistan Regional Government of Iraq. Trop Anim Health Prod. Oct;46(7):1297-301.

2013

  1. Pitesky M, Cataline K, Crossley B, Poulos M, Ramos G, Willoughby D, Woolcock P, Cutler G, Bland M, Tran J, Jackwood D, Allen L, Breitmeyer R, Jones A, Forsythe K, Sentíes-Cué CG, and Charlton B. 2013. Historical, spatial, temporal, and time-space epidemiology of very virulent infectious bursal disease in California: a retrospective study 2008-2011. Avian Dis. Mar;57(1):76-82.
  2. Jackwood DJ, and Stoute ST. 2013. Molecular evidence for a geographically restricted population of infectious bursal disease viruses. Avian Dis. 2013 Mar;57(1):57-64.
  3. Jackwood DJ. 2013. Multivalent virus-like-particle vaccine protects against classic and variant infectious bursal disease viruses. Avian Dis. Mar;57(1):41-50.
  4. Stoute ST, Jackwood DJ, Sommer-Wagner SE, Crossley BM, Woolcock PR, and Charlton BR. 2013. Pathogenicity associated with coinfection with very virulent infectious bursal disease and Infectious bursal disease virus strains endemic in the United States. J Vet Diagn Invest. May;25(3):352-8. doi: 10.1177/1040638713483538.
    Epub 2013 Apr 9.

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